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Table 2 Overall survival analyses according to delta RDW in 594 patients with ESCC

From: Clinical and prognostic significance of perioperative change in red cell distribution width in patients with esophageal squamous cell carcinoma

Variables

Univariate

Multivariate

HR

95% CI

P value

HR

95% CI

P value

delta RDW(≥ 0.44 vs.<0.44)

1.337

1.014–1.762

0.039

1.356

1.025–1.793

0.033

Sex (male vs.female)

1.204

0.793–1.829

0.383

   

Age (> 60 vs.≤60)

1.157

0.880–1.520

0.297

   

Pathology grade

      

Well differentiated

0.154

0.019–1.225

0.077

   

middle differentiated

0.260

0.036–1.871

0.181

   

Poorly differentiated

0.384

0.053–2.779

0.343

   

Undifferentiated

1.000

     

Depth of tumor

      

T1a–1b

0.486

0.257–0.920

0.027

0.524

0.225–1.217

0.133

T2

0.593

0.404–0.869

0.007

0.567

0.292–1.099

0.093

T3

1.000

     

Lymph node metastasis

      

N0

0.134

0.087–0.204

< 0.001

0.099

0.034–0.287

< 0.001

N1

0.250

0.167–0.375

< 0.001

0.263

0.171–0.405

< 0.001

N2

0.414

0.269–0.635

< 0.001

0.448

0.291–0.689

< 0.001

N3

1.000

     

Pathological stage

      

1a–1b

0.310

0.190–0.507

< 0.001

2.632

0.573–12.092

0.213

2a–2b

0.386

0.278–0.536

< 0.001

1.468

0.602–3.581

0.399

3a–3c

1.000

     

Vessel invasive (absence vs. presence)

1.808

1.369–2.388

< 0.001

1.194

0.884–1.612

0.248

Nerve infiltration (absence vs. presence)

1.899

1.447–2.493

< 0.001

1.483

1.112–1.977

0.007

Treatment regimen

      

S

1.131

0.692–1.848

0.623

   

 S + postoperative C

1.327

0.777–2.269

0.300

   

 S + postoperative CRT

1.000

     

delta NLR

1.016

0.973–1.061

0.473

   

delta PNI

1.008

0.986–1.030

0.499

   
  1. Abbreviations: S, surgery; C, chemotherapy; CRT, chemoradiotherapy