Table 1 Demographic and clinical data of 594 ESCC patients accroding to delta RDW
Charateristics | Total (N = 594), % | delta RDW | P value | ||
|---|---|---|---|---|---|
< 0.44 (N = 363), % | ≥ 0.44 (N = 231), % | ||||
Sex | Male | 513 (86.4) | 324 (89.3) | 189 (81.8) | 0.010 |
| Â | Female | 81 (13.6) | 39 (10.7) | 42 (18.2) | |
Age (years) | ≤ 60 | 270 (45.5) | 177 (48.8) | 93 (40.3) | 0.043 |
|  | > 60 | 324 (54.5) | 186 (51.2) | 138 (59.7) | |
Pathology grade | Well | 44 (7.4) | 26 (7.2) | 18 (7.8) | 0.972 |
| Â | middle | 403 (67.8) | 246 (67.8) | 157 (68.0) | |
| Â | Poorly | 145 (24.5) | 90 (24.7) | 55 (23.8) | |
| Â | Undifferentiated | 2 (0.3) | 1 (0.3) | 1 (0.4) | |
Depth of tumor | T1a–1b | 55 (9.3) | 37 (10.2) | 18 (7.8) | 0.420 |
| Â | T2 | 114 (19.2) | 73 (20.1) | 41 (17.7) | |
| Â | T3 | 425 (71.5) | 253 (69.7) | 172 (74.5) | |
Lymph node | N0 | 257 (43.3) | 154 (42.4) | 103 (44.6) | 0.922 |
| Â | N1 | 190 (32.0) | 118 (32.5) | 72 (31.2) | |
| Â | N2 | 99 (16.7) | 60 (16.5) | 39 (16.9) | |
| Â | N3 | 48 (8.1) | 31 (8.5) | 17 (7.4) | |
Pathological stage | 1a–1b | 99 (16.7) | 60 (16.5) | 39 (16.9) | 0.815 |
|  | 2a–2b | 202 (34.0) | 127 (35.0) | 75 (32.5) | |
|  | 3a–3c | 293 (49.3) | 176 (48.5) | 117 (50.6) | |
Vessel invasive | Yes | 179 (30.1) | 118 (32.5) | 61 (26.4) | 0.114 |
| Â | No | 415 (69.9) | 245 (67.5) | 170 (73.6) | |
Nerve infiltration | Yes | 216 (36.4) | 127 (35.0) | 89 (38.5) | 0.382 |
| Â | No | 378 (63.6) | 236 (65.0) | 142 (61.5) | |
Complications | Yes | 87 (14.6) | 30 (8.3) | 57 (24.7) | < 0.001 |
| Â | No | 507 (85.4) | 333 (91.7) | 174 (75.3) | |
Treatment regimen | S | 402 (67.7) | 236 (65.0) | 166 (71.9) | 0.163 |
|  |  S + postoperative C | 137 (23.1) | 93 (25.6) | 44 (19.0) | |
|  | S + postoperative CRT | 55 (9.3) | 34 (9.4) | 21 (9.1) | |
Preoperative RDW | Median | 12.8 (12.3–13.3) | 12.9 (12.4–13.4) | 12.7 (12.3–13.2) | 0.010 |
Postoperative RDW | Median | 13.2 (12.7–13.8) | 12.9 (12.5–13.4) | 13.7 (13.2–14.3) | < 0.001 |
Preoperative NLR | Median | 2.17 (1.60–2.89) | 2.17 (1.58–2.92) | 2.15 (1.63–2.88) | 0.378 |
Postoperative NLR | Median | 5.55 (4.00-7.17) | 5.67 (4.28–7.55) | 5.10 (3.63–6.77) | 0.022 |
Preoperative PNI | Median | 50.1 (47.0-53.5) | 49.9 (46.9–53.5) | 50.7 (47.2–53.5) | 0.107 |
Postoperative PNI | Median | 40.4 (37.0-43.6) | 39.7 (36.6–43.3) | 40.9 (37.5–44.7) | 0.002 |