From: Treatment of FIGO 2018 stage IIIC cervical cancer with different local tumor factors
Variables | T1 group (n = 1117) | T2a group (n = 1019) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
5-year OS | 5-year DFS | 5-year OS | 5-year DFS | |||||||||
HR | 95%CI | P | HR | 95%CI | P | HR | 95%CI | P | HR | 95%CI | P | |
Age(years) | 1.008 | 0.992–1.026 | 0.327 | 0.996 | 0.983–1.010 | 0.599 | 1.008 | 0.993–1.024 | 0.311 | 1.005 | 0.993–1.018 | 0.398 |
Histological type |  |  | 0.061 |  |  | 0.008 |  |  |  < 0.001 |  |  | 0.011 |
Squamous cell carcinoma | 1 | - | - | 1 | - | - | 1 | - | - | 1 | - | - |
Adenocarcinoma | 1.734 | 1.092–2.753 | 0.020 | 1.786 | 1.241–2.570 | 0.002 | 1.613 | 0.949–2.743 | 0.078 | 1.273 | 0.806–2.008 | 0.300 |
Adenosquamous cell carcinoma | 1.267 | 0.559–2.874 | 0.571 | 1.041 | 0.513–2.110 | 0.912 | 3.182 | 1.803–5.617 |  < 0.001 | 2.21 | 1.288–3.792 | 0.004 |
initiatreatment modality | Â | Â | 0.016 | Â | Â | 0.001 | Â | Â | 0.070 | Â | Â | 0.005 |
ARH | 1 | - | - | 1 | - | - | 1 | - | - | 1 | - | - |
R-CT | 1.569 | 0.756–3.254 | 0.226 | 1.349 | 0.727–2.501 | 0.343 | 1.085 | 0.674–1.748 | 0.736 | 1.073 | 0.737–1.562 | 0.714 |
NACT | 1.631 | 1.150–2.315 | 0.006 | 1.655 | 1.255–2.182 |  < 0.001 | 1.454 | 1.057–2.000 | 0.021 | 1.529 | 1.185–1.974 | 0.001 |