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Table 3 Levels of ERAP1 mRNA expression in tumor and non-tumor tissue according to sex, histological type of NSCLC and tumor stage

From: Down-regulation of ERAP1 mRNA expression in non-small cell lung cancer

Variable

Group

Non-tumor

Tumor

Mediana

CI95%b

Variabilityc

Mediana

CI95b

Variabilityc

Sex

Men

1.21

0.95

1.46

0.62

0.71

0.51

0.94

0.47

Women

1.00

0.76

1.27

0.54

0.80

0.58

1.04

0.52

Histological type of NSCLC

LUSC

1.15

0.75

1.55

0.80

0.70

0.47

0.96

0.39

LUAD

1.08

0.88

1.28

0.48

0.82

0.56

1.11

0.62

Other

1.20

0.66

2.12

0.72

0.70

0.37

1.03

0.51

Tumor stage

I

1.05

0.84

1.27

0.54

0.89

0.67

1.11

0.48

II

1.44

0.97

1.98

0.75

0.59

0.36

0.84

0.31

III

0.89

0.48

1.30

0.60

0.64

0.26

1.20

0.35

TNM

T1

0.98

0.68

1.31

0.56

0.90

0.59

1.26

0.61

T2

1.09

0.86

1.37

0.46

0.76

0.54

0.99

0.43

T3-T4

1.17

0.95

1.42

0.56

0.62

0.37

0.92

0.40

N0

1.12

0.90

1.34

0.62

0.78

0.62

0.96

0.47

N1

1.33

0.93

1.82

0.32

0.60

0.25

1.19

0.24

N2

0.59

0.10

1.12

0.35

0.82

0.24

1.43

0.52

  1. aHodges – Lehmann estimator
  2. bEstimated with bootstrap sampling
  3. c\(Sn\) statistic – typical difference between two randomly chosen persons
  4. LUSC Lung squamous cell carcinoma, LUAD Lung adenocarcinoma