Fig. 1
From: Chidamide enhances cytotoxicity of doxorubicin by promoting autophagy and apoptosis in breast cancer
CHI treatment inhibited BC cell proliferation and tumor growth. A, B CCK8 detection showed the proliferation ability of T47D (A) and MCF-7 (B) cells after treatment with different doses of CHI for 24 h. C, D Colony formation assay results showed T47D and MCF-7 cell proliferation after treatment with different doses of CHI. Data are expressed as means ± SD. ***P < 0.001 vs. 0 nM CHI. E Images of nude mouse xenografts regarding MCF-7 cells. F, G Tumor volumes in mice were measured every 5 days. Data are expressed as means ± SD. ***P < 0.001 vs. CHI. H, I Immunohistochemical detection showed the expression of Ki67 in the tumor tissues. Data are expressed as means ± SD. ***P < 0.001 vs. 0 nM CHI. Scal bar, 100 μm