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Fig. 7 | BMC Cancer

Fig. 7

From: Identification of ZBTB4 as an immunological biomarker that can inhibit the proliferation and invasion of pancreatic cancer

Fig. 7

Function of ZBTB4 in pancreatic cancer cells. A, B Protein expression levels of ZBTB4 were detected in pancreatic cancer cell lines. C Detection of ZBTB4 mRNA content in pancreatic cancer cell lines. D, E Detection of the efficiency of overexpression of ZBTB4 in Bxpc-3 cells. F–H Detection of the efficiency of silencing ZBTB4 in Panc-1 cells. CCK8 (I) and EdU (J) detect the effect of overexpression of ZBTB4 on the proliferation of Bxpc-3 cells. CCK8 (K) and EdU (L) detect the effect of silencing ZBTB4 on the proliferation of Panc-1 cells. M, N Transwell assays were used to detect the effects of overexpression or silencing of ZBTB4 on the migration and invasion ability of Bxpc-3 and Panc-1 cells. The data shown in this figure are representative of three biological replicate experiments. ns = p > 0.05, *p < 0.05, ** p < 0.01, ***p < 0.001

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