Table 4 Cox regression analysis revealed the risk factors for PFI in LAC patients

T stage

523

T1

175

Reference

T2

282

1.758 (1.276–2.422)

 < 0.001

1.428 (1.025–1.991)

0.035

T3

47

3.495 (2.199–5.556)

 < 0.001

2.593 (1.419–4.738)

0.002

T4

19

1.113 (0.444–2.791)

0.819

0.590 (0.190–1.834)

0.362

N stage

510

N0

343

Reference

N1

94

1.540 (1.118–2.122)

0.008

1.215 (0.692–2.135)

0.497

N2

71

1.498 (1.018–2.205)

0.040

0.560 (0.192–1.633)

0.288

N3

2

0.906 (0.127–6.485)

0.922

0.546 (0.062–4.845)

0.587

M stage

377

M0

352

Reference

M1

25

1.513 (0.855–2.676)

0.155

Pathologic stage

518

Stage I

290

Reference

Stage II

121

2.013 (1.478–2.742)

 < 0.001

1.404 (0.795–2.479)

0.242

Stage III

81

1.831 (1.257–2.669)

0.002

2.608 (0.841–8.085)

0.097

Stage IV

26

2.086 (1.189–3.657)

0.010

2.091 (1.064–4.110)

0.032

Gender

526

Female

280

Reference

Male

246

1.172 (0.901–1.526)

0.236

Age

516

 <  = 65

255

Reference

 > 65

261

1.023 (0.784–1.335)

0.867

SAAL1

526

Low

262

Reference

High

264

1.511 (1.159–1.970)

0.002

1.581 (1.195–2.091)

0.001