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Table 5 Univariate Cox regression and multivariate Cox regression analyses for progress-free survival of KIRC

From: Comprehensive analyses of A 12-metabolism-associated gene signature and its connection with tumor metastases in clear cell renal cell carcinoma

Variables

Univariate regression

Multivariate regression

HR

CI

P

HR

CI

P

TNM Stage

 I and II

 III and IV

6.69

4.66–9.59

 < 0.001

2.95

1.19–7.31

0.019

T Stage

 T1 or T2

 T3 or T4

4.41

3.18–6.11

 < 0.001

1.11

0.55–2.25

0.764

N Stage

 No

 N1

3.61

1.86–7.03

 < 0.001

0.94

0.45–1.94

0.863

M Stage

 M0

 M1

8.7

6.27–12.07

 < 0.001

4.1

2.4–7.01

 < 0.001

Gender

 Female

 Male

1.54

1.09–2.19

0.015

1.21

0.78–1.89

0.396

Age (years)

  < 65

  ≥ 65

1.17

0.85–1.61

0.341

the MAPs

 Risk Score

2.7

2.18–3.34

 < 0.001

1.89

1.4–2.55

 < 0.001

  1. aProgress-free survival (PFS) is the length of time during and after the treatment of a disease, such as cancer, that a patient lives with the disease but it does not get worse
  2. bThe variables in which P was below 0.05 in univariate Cox regression were involved into the further multivariate Cox regression
  3. cHazard ratio was estimated from Cox proportional hazard regression model
  4. dClinical information was derived from the TCGA-KIRC cohort
  5. eCI meant confidence interval of the estimated HR
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BMC Cancer

ISSN: 1471-2407

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