Fig. 5
Relationship between risk scores and clinicopathological features. The plots below show the association of risk scores with neoplasm histologic grades (A), T stages (B), N stages (C), M stages (D), and TNM stages (E) based on the TCGA-KIRC cohort. The Kaplan–Meier analysis of the MAPS regarding the stratified neoplasm histologic grades (F), TNM stages (G), T stages (H), M stages (I), and N stages (J) based on the TCGA-KIRC cohort. The expression level of 12 genes in the MAPS between samples with remote metastases and samples without remote metastases in the TCGA-KIRC cohort (K) and between ccRCC metastatic and primary ccRCC in the GSE22541 cohort(L). The gene-level transcription estimates were shown in a form of log2 (TPM + 1) (K). P was calculated using the χ2 test (the left panel of A, B, C, D, and E), one-way ANOVA with Tukey's multiple comparisons tests (the right panels of A, B, C, D, and E), log-rank test (F, G, H, I and J), and two-tailed Mann–Whitney test (K and L). For all the panels, * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, "ns" means no significance