Efficacy of curcumin for amelioration of radiotherapy-induced oral mucositis: a preliminary randomized controlled clinical trial

Table 2 Primary and secondary outcomes over the time

Variables	Comparing		Curcumin Mouthwash		Curcumin capsule		Placebo Mouthwash		Between group P-Value
Variables	Comparing		Mean Difference	Within group P-Value	Mean Difference	Within group P-Value	Mean Difference	Within group P-Value	Between group P-Value
WHO scale	W0	W1	0.385	0.018	0.33	0.20	0.36	0.100	0.981
		W2	1.61	0.001	1.16	0.001	0.92	0.051	0.150
		W3	2.23	0.001	1.70	0.001	0.72	0.070	0.002
	W1	W2	1.23	0.001	0.83	0.001	0.54	0.052	0.074
	W1	W3	1.84	0.001	1.40	0.001	0.36	0.340	< 0.001
	W2	W3	0.60	0.014	0.58	0.027	0.18	0.441	0.029
NRS	W0	W1	1.00	0.001	1.25	0.001	0.455	0.29	P < 0.01
		W2	3.20	0.001	3.25	0.001	1.63	0.001	P < 0.01
		W3	5.10	0.001	4.58	0.001	1.72	0.005	P < 0.01
	W1	W2	2.23	0.001	2.00	0.001	1.18	0.019	P < 0.01
	W1	W3	4.10	0.001	3.33	0.001	1.27	0.002	P < 0.01
	W2	W3	1.90	0.036	1.33	0.008	0.09	0.81	P < 0.01

ISSN: 1471-2407