Fig. 5
From: Exposure to nonanoic acid alters small intestinal neuroendocrine tumor phenotype
Prolonged nonanoic acid exposure could promote neuroendocrine differentiation. (A) Effect of nonanoic acid vs. vehicle (DMSO) treatment over 2 doubling times on cell proliferation (control = no drug), symbols depict individual measurements, line depicts mean, and bars depict standard deviation, **=p < 0,01. (B) Representative image of GOT1 cells exposed to nonanoic acid or vehicle (DMSO), for 3 weeks. Scale bar is equal to 100 μm. (C) Cell cycle analysis after 3 weeks nonanoic acid treatment versus DMSO in GOT1 cells, large bar depicts mean and error bar depict standard deviation, *=p < 0,05. (D) Effect of nonanoic acid treatment on synaptophysin expression in GOT1 cells (ADU = arbitrary densitometric units), symbol depicts mean, and bars represent standard deviation, *=p < 0,05