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Table 5 Health related quality of life by performance status and sex

From: Sex and gender differences in treatment intention, quality of life and performance status in the first 100 patients with periampullary cancer enrolled in the CHAMP study

 

Female

P-value

Male

P-valuea

ECOG

0

1

2

3

 

0

1

2

3

 

Global Health Score

 Median score

63

42

50

58

0.572

67

54

50

63

0.136

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

13 (32.5)

16 (40.0)

9 (22.5)

2 (5.0)

Physical functioning

 Median score

80

63

53

73

0.062

90

73

67

50

0.002

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

14 (33.3)

17 (40.5)

9 (21.4)

2 (4.8)

Role functioning

 Median score

67

33

50

58

0.336

92

50

67

58

0.058

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

14 (33.3)

17 (40.5)

9 (21.4)

2 (4.8)

Emotional functioning

 Median score

63

63

58

50

0.594

83

67

67

46

0.038

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

13 (32.5)

16 (40.0)

9 (22.5)

2 (5.0)

Cognitive functioning

 Median score

92

83

67

83

0.583

100

100

83

67

0.157

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

13 (32.5)

16 (40.0)

9 (22.5)

2 (5.0)

Social functioning

 Median score

50

50

50

83

0.525

67

67

67

33

0.022

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

13 (32.5)

16 (40.0)

9 (22.5)

2 (5.0)

Fatigue

 Median score

44

61

78

39

0.077

33

44

56

56

 < 0.001

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

14 (33.3)

17 (40.5)

9 (21.4)

2 (4.8)

Nausea

 Median score

8

17

17

8

0.503

0

0

0

17

0.474

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

14 (33.3)

17 (40.5)

9 (21.4)

2 (4.8)

Pain

 Median score

33

42

33

33

0.784

25

50

33

50

0.265

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

14 (33.3)

17 (40.5)

9 (21.4)

2 (4.8)

Dyspnea

 Median score

0

17

33

33

0.217

0

33

33

33

0.078

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

14 (33.3)

17 (40.5)

9 (21.4)

2 (4.8)

Insomnia

 Median score

33

33

0

66.7

0.626

33

0

0

33

0.418

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

14 (33.3)

17 (40.5)

9 (21.4)

2 (4.8)

Loss of appetite

 Median score

50

67

67

50

0.266

0

33

33

33

0.111

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

14 (33.3)

17 (40.5)

9 (21.4)

2 (4.8)

Constipation

 Median score

0

33

33

50

0.823

17

33

0

17

0.594

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

14 (33.3)

17 (40.5)

9 (21.4)

2 (4.8)

Diarrhea

 Median score

17

17

0

0

0.312

0

17

0

33

0.371

 N (%)

6 (18.8)

18 (56.3)

6 (18.8)

2 (6.3)

 

13 (32.5)

16 (40.0)

9 (22.5)

2 (5.0)

Financial difficulties

 Median score

0

0

0

17

0.493

0

0

0

0

0.493

 N (%)

6 (18.8)

17 (53.1)

7 (21.9)

2 (6.3)

 

13 (32.5)

16 (40.0)

9 (22.5)

2 (5.0)

  1. For functional scores, a high score indicates a high functional level, for symptom scores a high value indicates an increased severity of symptoms
  2. Abbreviation: ECOG Eastern Cooperative Oncology Group
  3. aNon-parametric test for continuous variables
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