Table 1 Demographic characteristics by sex and treatment intention
Adjuvant | Palliative | |||||
|---|---|---|---|---|---|---|
Women | Men | P-valuea | Women | Men | P-valuea | |
N (%) | 7 (28) | 18 (72) | 42 (56) | 33 (44) | ||
Age (years) | ||||||
Mean, ± SD | 66.5, 9.0 | 68.4, 5.6 | 0.745 | 68.1, 11.0 | 68.6, 7.3 | 0.741 |
(Range) | (51.7- 76.2) | (55.2–77.0) | (38.4—83.3) | (49.2- 79.5) | ||
ECOG at baseline | ||||||
0 | 5 (71) | 9 (50) | 0.173 | 6 (14) | 8 (24) | 0.436 |
1 | 2 (29) | 4 (22) | 22 (52) | 17 (52) | ||
2 | 0 | 5 (2) | 12 (29) | 5 (15) | ||
3 | 0 | 0 | 2 (5) | 3 (9) | ||
BMI (kg/m2) | ||||||
Underweight | 1 (14.3) | 0 (0.00) | 0.154 | 4 (10) | 1 (3) | 0.385 |
Normal weight | 4 (57.1) | 9 (50.0) | 26 (62) | 22 (67) | ||
Overweight | 2 (28.6) | 8 (44.4) | 8 (19) | 6 (18) | ||
Obese | 0 (0.00) | 1 (5.6) | 3 (7) | 4 (12) | ||
Mean, ± SD | 23.5, 3.8 | 24.9, 3.2 | 0.326 | 22.5, 5.2 | 25.1, 4.5 | 0.021 |
(range) | (18.4–29.8) | (19.8–32.7) | (16.7–43.0) | (17.0–39.4) | ||
Missing | 1 (2) | |||||
Civil Status | ||||||
Single | 0 (0) | 1 (6) | 0.443 | 5 (12) | 3 (9) | 0.697 |
Married | 5 (71) | 14 (78) | 27 (64) | 24 (73) | ||
Divorced/Widowed | 2 (29) | 3 (16) | 10 (24) | 6 (18) | ||
Diabetes mellitus | ||||||
No | 4 (57.1) | 13 (72) | 0.477 | 36 (86) | 23 (70) | 0.240 |
Yes | 3 (42.9) | 5 (28) | 4 (9) | 9 (27) | ||
Newly diagnosed | 0 | 0 | 2 (5) | 1 (3) | ||
Cardiac comorbidity | ||||||
No | 6 (86) | 17 (94) | 0.479 | 40 (95) | 26 (79) | 0.031 |
Yes | 1 (14) | 1 (6) | 2 (5) | 7 (21) | ||
Smoking | ||||||
No | 5 (71) | 7 (39) | 21 (50.0) | 17 (52) | ||
Yes, Current | 2 (29) | 2 (11) | 0.046 | 10 (24) | 5 (15) | 0.808 |
Yes, Former | 0 | 9 (50) | 10 (24) | 10 (30) | ||
Missing | 1 (2) | 1 (3.) | ||||
Other Cancer | ||||||
No | 4 (57) | 17 (94) | 0.025 | 30 (71) | 28 (85) | 0.171 |
Yes | 3 (43) | 1 (6) | 12 (29) | 5 (15) | ||
Neoadjuvant intent | ||||||
No | 5 (71) | 14 (78) | 0.744 | 35 (83) | 30 (91) | 0.497 |
Yes | 2 (29) | 4 (22) | 7 (17) | 3 (9) | ||
Chemotherapy backbone | ||||||
Gemcitabine | 2 (28.5) | 8 (44) | 0.375 | 8 (19) | 4 (15) | 0.732 |
Nabpaclitaxel | 0 | 1 (6) | 17 (40.5) | 14 (42.5) | ||
Oxaliplatin | 2 (28.5) | 4 (22) | 17 (40.5) | 14 (42.5) | ||
5-FU | 3 (43) | 5 (28) | 0 | 0 | ||
Location | ||||||
Pancreatic head | 4 (57) | 13 (72) | 0.477 | 23 (55) | 15 (45.5) | 0.427 |
Other | 3 (43) | 5 (28) | 19 (45) | 18 (54.5) | ||
Tumour stage | ||||||
Locally Advanced | - | - | 18 (43) | 10 (30) | 0.268 | |
Metastasised | - | - | 24 (57) | 23 (70) | ||