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Table 2 Cox multivariate analysis for overall and progression-free survival outcomes

From: Association of neutrophil–lymphocyte ratio with survival in peripheral early-stage non-small cell lung cancer after stereotactic body radiation therapy

 

Overall Survival

Progression-Free Survival

HR (95% CI)

P value

HR (95% CI)

P value

NLR

1.06 (1.02–1.10)

0.005a

1.05 (1.01–1.09)

0.01a

Age

  < 65

1 [Reference]

NA

1 [Reference]

NA

  ≥ 65

2.56 (1.47–4.46)

 < 0.001a

1.47 (0.92–2.36)

0.11

Gender

 Male

1 [Reference]

NA

1 [Reference]

NA

 Female

0.91 (0.66–1.26)

0.57

0.83 (0.60–1.13)

0.24

Race

 White

1 [Reference]

NA

1 [Reference]

NA

 Other

1.22 (0.59–2.51)

0.6

1.26 (0.62–2.56)

0.52

KPS

 70–100

1 [Reference]

NA

1 [Reference]

NA

  < 70

1.59 (1.12–2.24)

0.009a

1.43 (1.03–1.99)

0.03a

Histology

 Adenocarcinoma

1 [Reference]

NA

1 [Reference]

NA

 Squamous Cell

1.16 (0.81–1.65)

0.42

1.11 (0.80–1.56)

0.53

 NSCLC (NOS)

1.21 (0.72–2.02)

0.47

0.93 (0.55–1.55)

0.77

Site

 Left

1 [Reference]

NA

1 [Reference]

NA

 Right

0.93 (0.66–1.30)

0.66

0.87 (0.63–1.21)

0.41

T staging

 1

1 [Reference]

NA

1 [Reference]

NA

 2

1.45 (0.99–2.12)

0.06

1.39 (0.96–2.01)

0.09

Fractions

 1

1 [Reference]

NA

1 [Reference]

NA

 3

1.37 (0.97–1.94)

0.07

1.34 (0.97–1.87)

0.08

Smoking Status

 Current

1 [Reference]

NA

1 [Reference]

NA

 Former

0.80 (0.54–1.17)

0.24

0.75 (0.52–1.07)

0.11

 Never

0.80 (0.35–1.82)

0.6

0.67 (0.30–1.50)

0.32

Year of radiation

 2013 or earlier

1 [Reference]

NA

1 [Reference]

NA

 2013 or later

0.76 (0.54–1.07)

0.12

0.84 (0.60–1.17)

0.3

  1. aHR adjusted hazards ratio, CI confidence interval, KPS Karnofsky performance, NOS not otherwise specified
  2. astatistically significant