Table 1 Clinicopathological features of the 877 reviewed cases
Clinicopathological characteristics | Patients (N = 877) |
|---|---|
Age, years | |
 Median (range, interquartile range) | 69.0 (31–91, 63–74) |
Sex, N (%) | |
 Male | 439 (50.1) |
 Female | 438 (49.9) |
Smoking status, N (%) | |
 Never | 452 (51.5) |
 Current or ex- | 425 (48.5) |
Surgical procedure, N (%) | |
 Pneumonectomy | 1 (0.1) |
 Lobectomy | 431 (49.1) |
 Segmentectomy | 291 (33.2) |
 Wedge resection | 154 (17.6) |
Pathological invasive size, mm | |
 Median (range, interquartile range) | 10.0 (0–65, 4.0–18.0) |
Histological subtype, N (%) | |
 AIS | 156 (17.8) |
 MIA | 103 (11.7) |
 Lepidic predominance | 147 (16.8) |
 Papillary predominance | 397 (45.3) |
 Acinar predominance | 24 (2.7) |
 Micropapillary predominance | 17 (1.9) |
 Solid predominance | 33 (3.8) |
IASLC histological grade | |
 G1 | 145 (16.5) |
 G2 | 360 (41.0) |
 G3 | 113 (12.9) |
Pleural invasion, N (%) | |
 Pl0 | 781 (89.1) |
 Pl1 | 62 (7.1) |
 Pl2 | 20 (2.3) |
 Pl3 | 14 (1.6) |
Lymphatic invasion, N (%) | |
 Negative | 794 (90.5) |
 Positive | 83 (9.5) |
Vascular invasion, N (%) | |
 Negative | 743 (84.7) |
 Positive | 134 (15.3) |
Intrapulmonary metastasis, N (%) | |
 Negative | 859 (97.9) |
 PM1 | 18 (2.1) |
Pathological T status, N (%) | |
 Tis | 156 (17.8) |
 Tia (mi) | 103 (11.7) |
 T1a | 176 (20.1) |
 T1b | 226 (25.8) |
 T1c | 75 (8.6) |
 T2a | 98 (11.2) |
 T2b | 12 (1.4) |
 T3 | 31 (3.5) |
Genetic status, N (%) | |
 EGFR mutation | 404 (46.1) |
 KRAS mutation | 98 (11.2) |
 EGFR/KRAS wild type | 375 (42.8) |
Adjuvant chemotherapy, N (%) | |
 Done | 197 (22.5) |
 None | 680 (77.5) |
Recurrence, N (%) | |
 Negative | 807 (92.0) |
 Positive | 70 (8.0) |