Fig. 8From: The expression, immune infiltration, prognosis, and experimental validation of OSBPL family genes in liver cancerKnockdown of OSBPL3 restrained cell proliferation and migration. (a) The mRNA expression of OSBPL3 in six liver cancer cell lines. (b) Knockdown of OSBPL3 significantly reduced PLC/PRF/5 cell viability. (c) Knockdown of OSBPL3 after 24Â h induced a G2/M cell cycle arrest in PLC/PRF/5 cell. (d) Knockdown of OSBPL3 after 48Â h promoted PLC/PRF/5 cell apoptosis. (e) Knockdown of OSBPL3 after 48Â h activated the pro-apoptotic proteins. (f) Knockdown of OSBPL3 suppressed PLC/PRF/5 cell migrationBack to article page