Table 3 Clinicopathological features in the previously reported 16 cases in literature
Author | No. | Gender | Age | Tumor site | Size | Morphologic features | Risk class | Mutation | Outcome |
|---|---|---|---|---|---|---|---|---|---|
Heinrich [5] | 1 | M | 63 | stomach | NS | NA | NA | KIT exon 13 K642E + exon 17 N822H | DOD |
Rossi [6] | 2 | NA | NA | stomach | 0.8 cm | NA | NA | KIT exon 11 P551-M552delinsL + W557G | NA |
3 | NA | NA | small intestine | 1.7 cm | NA | NA | KIT exon 9 K509I + G510del | NA | |
4 | NA | NA | stomach | 2 cm | NA | NA | KIT exon 9 N505H + K509I | NA | |
Conca [7] | 5 | M | 68 | stomach | > 5 cm | mixed | High(NIH2002) | KIT exon 11 W557G + Y578C | NED, 36 m |
Kalfusova [8] | 6 | NA | NA | NA | NA | NA | NA | PDGFRA exon 14 M642T + N659H | NA |
Wong [9] | 7 | M | 45 | stomach | 3.5 cm | spindle | Moderate(AFIP) | KIT exon 11 W557-I563del + T574-Q575delinsK | Alive(NA for details), 23 m |
8 | F | 56 | small intestine | 19 cm | mixed | High(AFIP) | KIT exon 11 W557C + V560del | Metastasis after 3 years | |
9 | M | 49 | stomach | NS | spindle | NA | KIT exon 11 Y568D + Y578C | Alive(NA for details), 64 m | |
10 | F | 71 | NA | NA | spindle | NA | KIT exon 11 Y568D + L576P | NA | |
111 | M | 50 | stomach | NA | mixed | NA | PDGFRA exon 18 D842V + M844L | NA | |
12 | M | 70 | stomach | 35 cm | spindle | Moderate(AFIP) | KIT exon 17 N822K + K826Q | DOD, 7 years | |
13 | F | 43 | pelvis | NA | spindle | NA | KIT exon 11 K558N + V559A | NA | |
14 | M | 63 | stomach | 13 cm | spindle | High(AFIP) | KIT exon 11 W557G + K558E | NA | |
Haefliger [10] | 15 | M | NA | stomach | NA | spindle | NA | KIT exon 11 V559A + V560D | NA |
Bombac [11] | 16 | NA | NA | NA | NA | NA | NA | PDGFRA exon 14 K627E + N659H | NA |