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Table 2 The relationship between CONUT score and clinicopathological characteristics of the patients

From: Controlling Nutritional Status (CONUT) score is a prognostic marker in III-IV NSCLC patients receiving first-line chemotherapy

Variable

Total(n = 278)

CONUT score

χ2

P

 < 3(n = 164)

≥ 3(n = 114)

Gender

   

0.742

0.389

 Male

192(69.1%)

110(67.1%)

82(71.9%)

  

 Female

86(30.9%)

54(32.9%)

32(28.1%)

  

Age

   

8.537

0.003

 < 60

109(39.2%)

76(46.3%)

33(28.9%)

  

  ≥ 60

169(60.8%)

88(53.7%)

81(71.1%)

  

Smoking status

   

1.276

0.259

 Minimal/never

116(41.7%)

73(44.5%)

43(37.7%)

  

 Current/former

162(58.3%)

91(55.5%)

71(62.3%)

  

ECOG-PS

   

5.623

0.018

 0/1

160(57.6%)

104(63.4%)

56(49.1%)

  

 2

118(42.4%)

60(36.6%)

58(50.9%)

  

Histology subtype

   

3.272

0.195

 Squamous

113(40.6%)

60(36.6%)

53(46.5%)

  

 Adenocarcinoma

133(47.8%)

82(50.0%)

51(44.7%)

  

 others

32(11.5%)

22(13.4%)

10(8.8%)

  

TNM staging

   

7.504

0.006

 III

102(36.7%)

71(43.3%)

31(27.2%)

  

 IV

176(63.3%)

93(56.7%)

83(72.8%)

  

Chemotherapy regimens

   

5.691

0.233

 DP

32(11.5%)

17(10.4%)

15(13.2%)

  

 GP

97(34.9%)

55(33.5%)

42(36.8%)

  

 NP

37(13.3%)

23(14.0%)

14(12.3%)

  

 PC

83(29.9%)

56(34.1%)

27(23.7%)

  

 TP

29(10.4%)

13(7.9%)

16(14.0%)

  

CEA

   

0.764

0.382

 Normal

123(44.2%)

69(42.1%)

54(47.4%)

  

 High

155(55.8%)

95(57.9%)

60(52.6%)

  

CYF

   

0.750

0.386

 Normal

76(27.3%)

48(29.3%)

28(24.6%)

  

 High

202(72.7%)

116(70.7%)

86(75.4%)

  

NSE

   

0.638

0.424

 Normal

153(55.0%)

87(53.0%)

66(57.9%)

  

 High

125(45.0%)

77(47.0%)

48(42.1%)

  

SII

   

30.353

0.000

 < 984.72

140(50%)

60(37%)

80(70%)

  

 ≥ 984.72

138(50%)

104(63%)

34(30%)

  

PNI

   

53.448

0.000

  ≥ 48.95

129(46%)

106(64.0%)

23(20%)

  

 < 48.95

149(54%)

58(36.0%)

91(80%)

  
  1. ECOG-PS  Eastern Cooperative Oncology Group performance status, TNM  Tumor-node-metastasis, CONUT  Controlling nutritional status, SII  Systemic immune-inflammation index, PNI  Prognostic nutritional index, DP  Docetaxel plus cisplatin, GP  Gemcitabine plus cisplatin, NP  Vinorelbine plus cisplatin, PC  Pemetrexed plus cisplatin, TP  Paclitaxel plus cisplatin, CEA  Carcinoembryonic antigen, NSE  Neuron-specific enolase, CYF  Cytokeratin-19-fragment