Fig. 3

Distinct fragment length patterns of different sources of plasma mutations in PwHCC and healthy individuals. A and B Distribution of fragment length of sequencing reads carrying WBC-derived mutations (ALT) in PwHCC (A) and healthy individuals (B), as compared to their corresponding reference reads (REF). C and D Distribution of fragment lengths of sequencing reads carrying TDMs in PwHCC (C) and TDM shared mutations (D) detected in healthy participants, as compared to their corresponding reference reads (REF). E Distribution of fragment length of sequencing reads carrying variants of unknown sources (VUS) detected in plasma samples of HCC patients. F and G Distribution of fragment lengths of sequencing reads carrying LB-unique mutations in PwHCC (F) and healthy individuals (G), as compared to their corresponding reference reads (REF)