Fig. 2

Delineation of the functional states across different macrophage subsets. a t-SNE projection of cluster 0–4 macrophages, colored according to cell identity. b Heatmap showing the normalized single sample gene set enrichment analysis (ssGSEA) score for cancer- and immunological-related gene sets from the MSigDB hallmark collection across different macrophage subsets. c t-SNE projection of normalized ssGSEA score for representative hallmark and immune terms.