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Fig. 1 | BMC Cancer

Fig. 1

From: Feasibility and preliminary efficacy of a virtual reality intervention targeting distress and anxiety in primary brain tumor patients at the time of clinical evaluation: Study protocol for a phase 2 clinical trial

Fig. 1

Phase 2 study protocol flow diagram. Adult PBT patients will be recruited from the NOB NHS trial at the NIH. Patients who meet eligibility criteria will be recruited via email or in clinic and will complete informed consent to join the study. Baseline PROs and salivary stress biomarkers will be collected and patients will be stratified into low vs. high distress groups (based on DT scores). Research staff will meet with patients via telehealth to complete the initial VR intervention where participants will self-select a scenario to complete, followed by post-VR intervention assessments to assess acute effects. Patients can continue VR use at home for the remaining month on study and repeat post-VR intervention assessments will be collected at the 1 week and 4 weeks timepoints to assess subacute effects. A qualitative phone interview will be conducted 1 week following the initial VR intervention to assess patient satisfaction

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BMC Cancer

ISSN: 1471-2407

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