Variables | level | Low IFS score | Median IFS score | High IFS score | P value |
---|---|---|---|---|---|
 |  | N = 42 |  N = 110 |  N = 23 |  |
Age, year (mean ± SD) |  | 58.12 ± 9.78 | 56.56 ± 10.68 | 58.87 ± 10.80 | 0.521 |
Sex (%) | female | 14 (33.3) | 34 (30.9) | 6 (26.1) | 0.833 |
 | male | 28 (66.7) | 76 (69.1) | 17 (73.9) |  |
Hepatolithiasis (%) | no | 42 (100.0) | 106 (96.4) | 22 (95.7) | 0.436 |
 | yes | 0 (0.0) | 4 (3.6) | 1 (4.3) |  |
Diabetes (%) | no | 38 (90.5) | 101 (91.8) | 22 (95.7) | 0.758 |
 | yes | 4 (9.5) | 9 (8.2) | 1 (4.3) |  |
HBsAg (+) (%) | no | 22 (52.4) | 67 (60.9) | 15 (65.2) | 0.526 |
 | yes | 20 (47.6) | 43 (39.1) | 8 (34.8) |  |
Anti-HCV (%) | no | 42 (100.0) | 110 (100.0) | 22 (95.7) | 0.036 |
 | yes | 0 (0.0) | 0 (0.0) | 1 (4.3) |  |
Child-Pugh grade (%) | A | 37 (88.1) | 104 (94.5) | 17 (73.9) | 0.027 |
 | B | 2 (4.8) | 4 (3.6) | 4 (17.4) |  |
TBIL, mg/dL* | Â | 12.45 [10.03, 16.17] | 11.90 [9.83, 14.35] | 10.30 [8.85, 12.25] | 0.153 |
ALT, IU/L* | Â | 18.50 [14.00, 25.90] | 21.90 [14.00, 31.08] | 28.00 [15.75, 46.00] | 0.151 |
AST, IU/L* | Â | 22.15 [17.00, 27.88] | 22.95 [17.25, 31.75] | 31.80 [23.05, 42.00] | 0.012 |
GGT, IU/L* | Â | 49.00 [28.25, 86.25] | 73.50 [38.25, 154.75] | 92.00 [55.00, 199.00] | 0.079 |
HgB, g/L (mean ± SD) |  | 136.05 ± 15.16 | 134.75 ± 13.86 | 124.65 ± 18.64 | 0.007 |
PT, second* | Â | 11.55 (1.17) | 11.65 (0.90) | 12.22 (1.19) | 0.027 |
ALB, g/L (mean ± SD) |  | 42.69 ± 5.27 | 42.36 ± 3.37 | 40.00 ± 3.78 | 0.021 |
PLT, ×109/L* |  | 162.00 [133.50, 199.00] | 186.50 [146.25, 242.50] | 185.00 [136.50, 223.00] | 0.054 |
WBC, ×109/L* |  | 5.98 [4.66, 6.82] | 6.08 [5.03, 7.46] | 6.13 [5.04, 8.27] | 0.428 |
AFP, µg/L* |  | 3.50 [1.90, 6.05] | 3.05 [2.12, 5.70] | 6.60 [2.40, 21.00] | 0.208 |
CEA, µg/L* |  | 2.30 [1.40, 3.65] | 2.90 [2.00, 6.10] | 3.30 [1.55, 4.70] | 0.024 |
CA199, IU/mL* | Â | 36.45 [18.35, 124.85] | 69.75 [24.20, 670.12] | 45.20 [16.65, 171.60] | 0.104 |
Perioperative transfusion (%) | no | 37 (88.1) | 96 (87.3) | 19 (82.6) | 0.804 |
 | yes | 5 (11.9) | 14 (12.7) | 4 (17.4) |  |
Anatomic resection (%) | no | 30 (71.4) | 71 (64.5) | 13 (56.5) | 0.472 |
 | yes | 12 (28.6) | 39 (35.5) | 10 (43.5) |  |
Major resection (%) | no | 30 (71.4) | 74 (67.3) | 18 (78.3) | 0.559 |
 | yes | 12 (28.6) | 36 (32.7) | 5 (21.7) |  |
Cirrhosis (%) | no | 31 (73.8) | 89 (80.9) | 15 (65.2) | 0.223 |
 | yes | 11 (26.2) | 21 (19.1) | 8 (34.8) |  |
Tumor diameter, cm (mean ± SD) |  | 5.55 ± 3.54 | 6.58 ± 3.60 | 8.02 ± 3.76 | 0.031 |
Multiple tumors (%) | no | 34 (81.0) | 70 (63.6) | 18 (78.3) | 0.073 |
 | yes | 8 (19.0) | 40 (36.4) | 5 (21.7) |  |
Satellite nodules (%) | no | 27 (64.3) | 58 (52.7) | 16 (69.6) | 0.203 |
 | yes | 15 (35.7) | 52 (47.3) | 7 (30.4) |  |
Tumor capsule (%) | no | 40 (95.2) | 100 (90.9) | 21 (91.3) | 0.747 |
 | complete | 1 (2.4) | 7 (6.4) | 2 (8.7) |  |
 | incomplete | 1 (2.4) | 3 (2.7) | 0 (0.0) |  |
Tumor differentiation (%) | low | 3 (7.1) | 9 (8.2) | 3 (13.0) | 0.466 |
 | median | 37 (88.1) | 96 (87.3) | 17 (73.9) |  |
 | high | 2 (4.8) | 5 (4.5) | 3 (13.0) |  |
Adjacent tissue invasion (%) | no | 40 (95.2) | 105 (95.5) | 20 (87.0) | 0.267 |
 | yes | 2 (4.8) | 5 (4.5) | 3 (13.0) |  |
MVI (%) | no | 35 (83.3) | 88 (80.0) | 21 (91.3) | 0.425 |
 | yes | 7 (16.7) | 22 (20.0) | 2 (8.7) |  |
LNM (%) | no | 40 (95.2) | 96 (87.3) | 19 (82.6) | 0.242 |
 | yes | 2 (4.8) | 14 (12.7) | 4 (17.4) |  |