Table 3 Effectiveness of colposcopy in distinguishing <HSIL from HSIL+
Study | TP | FP | FN | TN | Total | Sensitivity (95% CI) | Specificity (95% CI) |
|---|---|---|---|---|---|---|---|
Ghosh et al., 2014 [24] | 120 | 194 | 108 | 2044 | 2466 | 0.53 (0.46–0.59) | 0.91 (0.90–0.92) |
Spinillo et al., 2014 [28] | 195 | 91 | 340 | 1900 | 2526 | 0.36 (0.32–0.41) | 0.95 (0.94–0.96) |
Zhao et al., 2015 [31] | 36 | 20 | 50 | 1891 | 1997 | 0.42 (0.31–0.53) | 0.99 (0.98–0.99) |
Coronado et al., 2016 [22] | 33 | 40 | 8 | 362 | 443 | 0.80 (0.65–0.91) | 0.90 (0.87–0.93) |
Li et al., 2017 [8] | 63 | 17 | 36 | 409 | 525 | 0.64 (0.53–0.73) | 0.96 (0.94–0.98) |
Fan et al., 2018 [9] | 452 | 33 | 179 | 1598 | 2262 | 0.72 (0.68–0.75) | 0.98 (0.97–0.99) |
Liu et al., 2018 [31] | 30 | 42 | 0 | 184 | 256 | 1.00 (0.88–1.00) | 0.81 (0.76–0.86) |
Ruan et al., 2020 [27] | 282 | 82 | 219 | 1245 | 1828 | 0.56 (0.52–0.61) | 0.94 (0.92–0.95) |
Del Pino et al., 2021 [23] | 69 | 29 | 54 | 150 | 302 | 0.56 (0.47–0.65) | 0.84 (0.78–0.89) |
Li et al., 2021 [25] | 163 | 12 | 135 | 185 | 495 | 0.55 (0.49–0.60) | 0.94 (0.90–0.97) |
Liu et al., 2021 [26] | 127 | 46 | 43 | 771 | 987 | 0.75 (0.67–0.81) | 0.94 (0.93–0.96) |
Zhang et al., 2022 [33] | 485 | 89 | 130 | 1134 | 1838 | 0.79 (0.75–0.82) | 0.93 (0.91–0.94) |
Maffini et al., 2022 [34] | 64 | 0 | 14 | 24 | 102 | 0.82 (0.72–0.90) | 1.00 (0.86–1.00) |
Wei et al., 2022 [29] | 760 | 332 | 323 | 1002 | 2417 | 0.70 (0.67–0.73) | 0.75 (0.73–0.77) |
Stuebs et al., 2022 [32] | 2082 | 644 | 596 | 1456 | 4778 | 0.78 (0.76–0.79) | 0.69 (0.67–0.71) |