Table 1 Patient and tumor characteristics in patients with BRAF-mutated

Age

  < 65 years

20

21

0.208

0.648

  ≥ 65 years

11

9

Gender

 Male

17

17

0.021

0.886

 Female

14

13

Ecog

  < 2

27

27

0.126

0.722

  ≥ 2

4

3

Tumor site

 Multi-sides

2

0

4.173

0.206

 Right colon

13

9

 Left colon

9

8

 Rectum

7

13

Histologic grade

 Missing

4

3

0.283

1

 Low grade

11

12

 High grade

16

15

Number of metastatic sites

 Single

17

14

0.407

0.523

 Multiple

14

16

MMR Status

 Missing

10

8

3.227

0.229

 dMMR

3

0

 pMMR

18

22

Primary tumor surgery

 No

10

16

2.769

0.096

 Yes

21

14

Intestinal obstruction

 No

29

27

0.109

0.742

 Yes

5

3

Liver metastases

 No

14

14

0.014

0.906

 Yes

17

16

Lung metastases

 No

19

22

1.003

0.316

 Yes

12

8

Peritoneal metastasis

 No

27

24

0.162

0.687

 Yes

4

6

Distant lymph node metastases

 No

24

19

1.454

0.228

 Yes

7

11