Table 2 Relationship between SP expression and clinicopathological features of breast cancer patients with HR-ve versus HR + ve tumors
Parameters | HR-ve (n = 77) | HR + ve (n = 67) | ||||
|---|---|---|---|---|---|---|
Low SP | High SP | p-value | Low SP | High SP | p-value | |
Age (Years) | 51.77 ± 12.97 | 49.97 ± 10.76 | 0.529 | 52.26 ± 12.50 | 52.21 ± 8.95 | 0.984 |
Tumor grade I II III | 0 (0) 7 (14.9) 40 (85.1) | 0 (0) 4 (13.3) 26 (86.7) | 1.000 | 4 (10.5) 13 (34.2) 21 (55.3) | 3 (10.3) 11 (37.9) 15 (51.7) | 0.936 |
Tumor volume (cm 3 ) | 62.28 ± 105.25 | 34.85 ± 47.08 | 0.184 | 33.53 ± 47.53 | 22.67 ± 30.91 | 0.289 |
TNM Stage I II III IV | 3 (6.5) 16 (34.8) 16 (34.8) 11 (23.9) | 1 (3.4) 3 (10.3) 12 (41.4) 13 (44.8) | 0.056 | 1 (2.6) 9 (23.7) 11 (28.9) 17 (44.7) | 2 (7.1) 9 (32.1) 9 (32.1) 8 (28.6) | 0.527 |
TNM stage I/II III/IV | 19 (41.3) 27 (58.7) | 4 (13.8) 25 (86.2) | 0.020 | 10 (26.3) 28 (73.7) | 11 (39.3) 17 (60.7) | 0.295 |
T stage T1 T2 T3 T4 | 3 (6.4) 28 (59.6) 12 (25.5) 4 (8.5) | 3 (10.0) 9 (30.0) 13 (43.3) 5 (16.7) | 0.081 | 3 (7.9) 19 (50.0) 11 (28.9) 5 (13.2) | 2 (6.9) 18 (62.1) 8 (27.6) 1 (3.4) | 0.569 |
pT T1/T2 T3/T4 | 31 (72.1) 16 (47.1) | 12 (27.9) 18 (52.9) | 0.035 | 22 (52.4) 16 (64.0) | 20 (47.6) 9 (36.0) | 0.447 |
 N stage N0 N1 N2 N3 | 18 (39.1) 7 (15.2) 12 (26.1) 9 (19.6) | 2 (7.1) 8 (28.6) 4 (14.3) 14 (50.0) | 0.002 | 12 (32.4) 6 (16.2) 8 (21.6) 11 (29.7) | 8 (28.6) 10 (35.7) 5 (17.9) 5 (17.9) | 0.332 |
M stage M0 M1 | 35 (76.1) 11 (23.9) | 16 (55.2) 13 (44.8) | 0.077 | 21 (55.3) 17 (44.7) | 20 (71.4) 8 (28.6) | 0.208 |
Axillary lymph nodes metastasis Negative Positive | 18 (39.1) 28 (60.9) | 2 (6.9) 27 (93.1) | 0.003 | 12 (31.6) 26 (68.4) | 9 (31.0) 20 (69.0) | 1.000 |
Lymphatic/vascular invasion Negative Positive | 18 (41.9) 25 (58.1) | 6 (20.7) 23 (79.3) | 0.077 | 12 (31.6) 26 (28.4) | 11 (39.3) 17 (60.7) | 0.604 |
HER2 status Negative Positive | 24 (51.1) 23 (48.9) | 11 (36.7) 19 (63.3) | 0.248 | 11 (28.9) 27 (71.1) | 20 (69.0) 9 (31.0) | 0.001 |
DCIS Absent Present | 16 (36.4) 28 (63.6) | 6 (20.0) 24 (80.0) | 0.195 | 7 (18.4) 31 (81.6) | 3 (10.3) 26 (89.7) | 0.495 |
Family History No Yes | 28 (80.0) 7 (20.0) | 11 (61.1) 7 (38.9) | 0.191 | 28 (84.8) 5 (15.2) | 23 (79.3) 6 (20.7) | 0.741 |
Ki-67 Low High | 21 (44.7) 26 (55.3) | 14 (46.7) 16 (53.3) | 1.000 | 28 (73.7) 10 (26.3) | 20 (69.0) 9 (31.0) | 0.786 |
NK1R Low High | 33 (70.2) 14 (29.8) | 12 (40.0) 18 (60.0) | 0.010 | 24 (63.2) 14 (68.8) | 22 (75.9) 7 (24.1) | 0.300 |
PKM2 Low High | 24 (58.5) 17 (41.5) | 18 (69.2) 8 (30.8) | 0.444 | 26 (68.4) 12 (31.6) | 10 (35.7) 18 (64.3) | 0.012 |