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Fig. 7 | BMC Cancer

Fig. 7

From: Expression of substance P, neurokinin 1 receptor, Ki-67 and pyruvate kinase M2 in hormone receptor negative breast cancer and evaluation of impact on overall survival

Fig. 7

Kaplan–Meier survival curves of overall survival for PKM2 expression in patients with breast cancer. a). Overall survival based on PKM2 expression in pooled samples. b). Overall survival based on PKM2 expression in HER2-enriched cases. c). Overall survival based on PKM2 expression in luminal A cases. d). Overall survival based on PKM2 expression in triple positive cases. e). Overall survival based on PKM2 expression in triple negative cases. f). Overall survival based on PKM2 expression in HR-ve cases. g). Overall survival based on PKM2 expression in HR + ve cases. h). Overall survival based on PKM2 expression HR-ve cases with low SP expression level. i). Overall survival based on PKM2 expression in HR-ve cases with positive DCIS history. 

Significant differences were calculated using the log-rank test. p < 0.05 is statistically significant

Abbreviations: PKM2: pyruvate kinase M2; HER2: human epidermal growth factor receptor type 2; HR-ve: hormone receptor negative; HR + ve: hormone receptor positive; SP: substance P; DCIS: ductal carcinoma in situ.

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BMC Cancer

ISSN: 1471-2407

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