| HLI categories | ||||||||
---|---|---|---|---|---|---|---|---|---|
Baseline Characteristics | 1 (n = 541) | 2 (n = 1023) | 3 (n = 1352) | 4 (n = 851) | p-value | ||||
Demographic Characteristics | |||||||||
 Age at Baseline (years) | 60.8 | (4.2) | 61.3 | (4.2) | 61.3 | (4.2) | 61.5 | (4.3) | 0.002 |
 Male Sex (yes) | 402 | (74.3) | 597 | (58.4) | 598 | (44.2) | 266 | (31.3) |  < 0.001 |
 Educational Level | |||||||||
  Primary School | 155 | (28.7) | 308 | (30.1) | 352 | (26.0) | 217 | (25.5) | 0.18 |
  Lower Vocational School | 109 | (20.1) | 205 | (20.0) | 298 | (22.0) | 190 | (22.3) |  |
  Intermediate Vocational School | 184 | (34.0) | 353 | (34.5) | 493 | (36.5) | 329 | (38.7) |  |
  Higher Vocational School or University | 89 | (16.5) | 150 | (14.7) | 205 | (15.2) | 113 | (13.3) |  |
  Unknown | 4 | (0.7) | 7 | (0.7) | 4 | (0.3) | 2 | (0.2) |  |
Lifestyle characteristics | |||||||||
 Energy intake (kcal/day) | 2057 | (537) | 1958 | (521) | 1886 | (505) | 1851 | (460) |  |
 Dietary fibre intake (g/day) | 23.0 | (5.4) | 25.3 | (5.8) | 27.7 | (6.7) | 29.9 | (6.6) |  |
 Red and processed meat intake (g/day) | 115.4 | (40.5) | 105.6 | (40.0) | 98.3 | (39.6) | 82.9 | (41.1) |  |
 Ratio of poly-unsaturated/saturated fat | 0.45 | (0.21) | 0.50 | (0.24) | 0.56 | (0.27) | 0.64 | (0.30) |  |
 Intake of transfats (g/day) | 3.23 | (1.55) | 3.05 | (1.15) | 2.87 | (1.05) | 2.63 | (0.90) |  |
 Glycaemic load | 122.4 | (28.9) | 121.3 | (27.3) | 117.9 | (26.6) | 116.6 | (24.7) |  |
 Vegetables and fruits intake (g/day) | 272 | (111) | 323 | (129) | 383 | (146) | 446 | (157) |  |
 Use of alcohol (yes) | 515 | (95.2) | 855 | (83.6) | 994 | (73.5) | 519 | (61.0) |  |
 Intake of alcohol (consumers only, g/day) | 23.4 | (19.8) | 15.6 | (14.9) | 10.9 | (12.2) | 6.0 | (7.6) |  |
 Cigarette smoking | |||||||||
  Never | 21 | (3.9) | 191 | (18.7) | 576 | (42.6) | 574 | (67.5) |  |
  Former | 157 | (29.0) | 431 | (42.1) | 555 | (41.1) | 247 | (29.0) |  |
  Current | 363 | (67.1) | 401 | (39.2) | 221 | (16.3) | 30 | (3.5) |  |
 Number of cigarettes (users only, /day)a | 20 | (15–25) | 15 | (10–20) | 10 | (7–15) | 8 | (5–10) |  |
 Years of cigarette smoking (users only) | |||||||||
 Non-occupational physical activity (min/day)a | 34.3 | (19.3–49.3) | 47.1 | (30.0–75.7) | 64.3 | (41.4–94.3) | 88.6 | (60.0–124.3) |  |
 Body mass index (kg/m2) | 26.4 | (3.1) | 25.4 | (3.1) | 24.9 | (2.9) | 23.5 | (2.6) |  |
 Intake of sodium (mg/day) | 2364 | (629) | 2319 | (623) | 2319 | (613) | 2273 | (605) | 0.01 |
 Intake of potassium (mg/day) | 3420 | (559) | 3462 | (558) | 3544 | (599) | 3596 | (610) |  < 0.001 |
 Intake of magnesium (mg/day) | 293 | (51) | 303 | (50) | 315 | (57) | 326 | (58) |  < 0.001 |
Medical characteristics | |||||||||
 History of Hypertension and/or History of Antihypertensive Drug Use (yes) | 159 | (29.4) | 321 | (31.4) | 447 | (33.1) | 272 | (32.0) | 0.47 |
 History of Diabetes (yes) | 17 | (3.1) | 29 | (2.8) | 44 | (3.3) | 33 | (3.9) | 0.65 |
 History of Kidney Stones (yes) | 47 | (8.7) | 107 | (10.5) | 107 | (7.9) | 65 | (7.6) | 0.10 |
 Familial History of Cancer (yes) | 236 | (43.6) | 403 | (39.4) | 530 | (39.2) | 355 | (41.7) | 0.36 |
 Familial History of Renal Cancer (yes) | 3 | (0.6) | 14 | (1.4) | 18 | (1.3) | 5 | (0.6) | 0.17 |