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Fig. 6 | BMC Cancer

Fig. 6

From: Novel fusion protein PK5-RL-Gal-3C inhibits hepatocellular carcinoma via anti-angiogenesis and cytotoxicity

Fig. 6

PK5-RLGal-3C induces G1 cell cycle arrest. After treated with 4 μmol/l rPK5-RL-Gal-3C for 48 h, HepG2 cells were stained with PI and then analyzed with flow cytometer. A rPK5-RL-Gal-3C treatment induced G1 cell cycle arrest on HepG2 cells. Western-blotting was performed to analyze the expression of proteins associated with cell cycle arrest. B rPK5-RL -Gal-3C treatment down-regulated the protein expression of Cyclin D1, Cyclin D3, and CDK4, but up-regulated the protein expression of p21 and p27. Significant differences are denoted by *** for p < 0.001

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BMC Cancer

ISSN: 1471-2407

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