Table 3 Differential diagnostic efficiency of 18F-FDG PET metabolic parameters and clinical variables and model between nonmetastatic gallbladder cancer and cholecystitis
Parameters | Cut-off | AUC (95%CI) | Sensitivity (95%CI) | Specificity (95%CI) | PPV (95%CI) | NPV (95%CI) |
|---|---|---|---|---|---|---|
SUVmax | 12.5 | 0.677 (0.577–0.777) | 0.398 (0.297–0.508) | 0.941 (0.789–0.990) | 0.946 (0.805–0.991) | 0.376 (0.276–0.489) |
SUVmean | 7.0 | 0.684 (0.585–0.783) | 0.398 (0.297–0.508) | 0.912 (0.752–0.977) | 0.921 (0.775–0.979) | 0.369 (0.268–0.482) |
SUVpeak | 9.8 | 0.690 (0.593–0.787) | 0.398 (0.297–0.508) | 0.912 (0.752–0.977) | 0.921 (0.775–0.979) | 0.369 (0.268–0.482) |
SUVR | 5.9 | 0.698 (0.599–0.796) | 0.341 (0.245–0.451) | 0.971 (0.829–0.998) | 0.968 (0.815–0.998) | 0.363 (0.266–0.471) |
Cholecystolithiasis | - | 0.556 (0.438–0.675) | 0.966 (0.897–0.991) | 0.147 (0.055–0.318) | 0.746 (0.654–0.820) | 0.625 (0.259–0.898) |
Fever | - | 0.597 (0.477–0.717) | 0.989 (0.929–0.999) | 0.206 (0.093–0.384) | 0.763 (0.672–0.836) | 0.875 (0.467–0.993) |
CEA > 5ng/ml | - | 0.652 (0.553–0.752) | 0.364 (0.266–0.474) | 0.941 (0.789–0.990) | 0.941 (0.789–0.990) | 0.364 (0.266–0.474) |
Model | - | 0.899 (0.840–0.958) | 0.909 (0.824–0.957) | 0.735 (0.553–0.865) | 0.899 (0.812–0.950) | 0.758 (0.574–0.883) |