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Table 2 Multivariate linear regression analysis of clinical parameters with BCMA expression

From: The exploration of B cell maturation antigen expression in plasma cell dyscrasias beyond multiple myeloma

 

BCMA positive rate

Log BCMA MFI

 

Coefficient

95% CI

P

Coefficient

95% CI

P

Gender

-1.209

-7.016 - 4.598

0.682

0.054

-0.034 - 0.142

0.225

Age

-0.071

-0.395 - 0.253

0.667

-0.004

-0.009 - 0.001

0.135

History of therapy

4.435

-3.046 - 11.916

0.244

0.080

-0.032 - 0.191

0.162

Hemoglobin

-0.277

-0.398 - -0.156

< 0.001*

-0.003

-0.004 - -0.001

0.005*

Serum albumin

0.481

0.056 - 0.905

0.027*

0.003

-0.004 - 0.009

0.385

Serum calcium

7.069

-0.223 - 14.362

0.057

0.053

-0.057 - 0.163

0.344

Serum creatinine

0.008

-0.023 - 0.039

0.606

< 0.001

0 - 0.001

0.183

Serum β2-M

-0.144

-0.592 - 0.304

0.528

-0.005

-0.012 - 0.002

0.150

Serum LDH

0.008

-0.005 - 0.02

0.242

< 0.001

-0.0004 - 0.0003

0.113

Auto-HSCT

-1.405

-15.763 - 12.954

0.847

-0.085

-0.295 - 0.126

0.429

BCMA CART trial

-9.582

-26.432 - 7.267

0.264

0.098

-0.145 - 0.34

0.427

  1. β2-M, β2-microglobulin, LDH Lactic dehydrogenase, BCMA B cell maturation antigen, MFI mean fluorescence intensity, Auto-HSCT, Autologous hematopoietic stem cell transplantation
  2. *: p values less than 0.05 (two-tailed) were considered statistically significant