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Table 2 Differently expressed genes. RT = animals treated with RT 8 Gy × 2; RT + anti-C1-INH = animals treated with RT 8 Gy × 2 + anti-C1-INH; Anti-C1-INH = animals treated with anti-C1-INH; Control = animals inoculated with tumor cells but without no further treatment. The gene expression was increased in the first-mentioned group in the column “Group” if fold change > 0; and decreased if fold change was < 0; ie fold change > 0 comparing RT versus Control means that the expression was increased in irradiated animals compared to control animals

From: Combined anti-C1-INH and radiotherapy against glioblastoma

Gene name

Fold change (log2)

p-value (corrected for multiple comparisons)

Groups

C1r

2,565,566,234

4,27E-07

RT + anti-C1-INH versus Control

C1s

3,449,858,746

4,04E-09

RT + anti-C1-INH versus Control

C1s

2,684,553,496

1,99E-07

RT versus Control

C2

2,898,202,831

7,74E-08

RT + anti-C1-INH versus Control

C2

2,181,478,879

3,50E-06

RT versus Control

C3

-4,42,863,084

1,42E-05

Control versus Anti-C1-INH

C3

3,750,450,877

2,45E-04

RT + anti-C1-INH versus Control

C3

3,024,466,599

1,01E-03

RT versus Control

C4b

3,889,746,413

9,18E-09

RT + antiC1-INH versus Control

C4b

2,689,104,385

4,80E-06

RT versus Control

Cd55

2,270,818,549

9,66E-06

Control versus Anti-C1-INH

Cd55

-2,384,966,084

0,000,275,229

RT + anti-C1-INH versus Control