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Table 1 Patient’s Demographics and Cancer Treatment Characteristics Based on Transfusion Status

From: Pre-operative anemia and peri-operative transfusion are associated with poor oncologic outcomes in cancers of the esophagus: potential impact of patient blood management on cancer outcomes

 

Transfused (n = 78)

Not Transfused (n = 270)

p-value

Age *

67 ± 9 years

65 ± 9 years

0.09

Gender

12 (15%) Female

62 (23%) Female

0.16

66 (85%) Male

208 (77%) Male

Anemic at Diagnosis**

120/289 (42%)

41 (61%)

79 (36%)

0.0002

Clinical T Stage

1 8 (12%)

2 7 (10%)

3 51 (75%)

4 2 (3%)

1 31 (14%)

2 32 (14%)

3 164 (72%)

4 0 (0%)

0.26

Tumor Histology

12 (16%) Squamous

65 (84%) Adenoca

37 (11%) Squamous

288 (89%) Adenoca

0.33

Treated with NARx

53 (68%)

163 (60%)

0.70

Diagnosis to OR (days)*,$

130 ± 2 days

136 ± 39 days

0.39

Complete Response (CR) to NARx$

12 (23%)

66 (40%)

P = 0.021

Anemic Pre-operative**

216/338 (64%)

67 (86%)

149 (57%)

 < 0.0001

Estimated Blood Loss (EBL)*

383 ± 274 ml

257 ± 166 ml

 < 0.0001

Pathologic/Surgical T Stage

0 13 (17%)

1 15 (19%)

2 17 (22%)

3 30 (38%)

4 2 (3%)

In-Situ 1 (1%)

0 69 (26%)

1 70 (26%)

2 44 (16%)

3 83 (31%)

4 0 (0%)

In-Situ 3 (1%)

P = 0.032

Lymph Node Status

50 (64%) Negative

172 (64%) Negative

1.00

28 (36%) Positive

97 (36%) Positive

Hospital Length of Stay *

19 ± 20 days

9 ± 4 days

 < 0.0001

  1. * Mean + S.D. reported
  2. ** anemia diagnosed as Hb < 12.0 g/dL for women and Hb < 13.5 g/dL for men
  3. $for cases treated with neoadjuvant chemo/radiotherapy only