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Table 3 PD-L1 22C3 CPS associated with immune cell densities

From: Characterisation of tumour-immune phenotypes and PD-L1 positivity in squamous bladder cancer

 

PD-L1 22C3 CPSb

na

 < 10

 ≥ 10

P-valuec

Immune cell markers:

 CD3

  ≤ 582.3/mm2

49

46

3

0.019

  > 582.3/mm2

48

37

11

 CD4

  ≤ 141.5/mm2

48

44

4

0.061

  > 141.5/mm2

45

35

10

 CD8

  ≤ 291.6/mm2

46

43

3

0.020

  > 291.6/mm2

46

35

11

 CD68

  ≤ 493.0/mm2

50

46

4

0.051

  > 493.0/mm2

45

35

10

 CD79A

  ≤ 85.9/mm2

50

45

5

0.200

  > 85.9/mm2

47

38

9

 CD163

  ≤ 462.1/mm2

51

47

4

0.046

  > 462.1/mm2

45

35

10

 Perforin

  ≤ 9.0/mm2

43

39

4

0.271

  > 9.0/mm2

40

33

7

  1. aOnly patients with primary sq-BLCA were included; bCombined positive score (CPS) according to Kulangara et al. (25); cPearson’s chi-square test; Significant P-values are marked in bold face. Please note: sample numbers may vary between analyses due to limitations of usable TMA cores depending on the staining
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BMC Cancer

ISSN: 1471-2407

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