Table 4 Imaging features of breast cancers with and without pathogenic mutations
Variable | Pathogenic N = 17 | No Pathogenic N = 47 | No. of all | P value |
|---|---|---|---|---|
MG | ||||
 Breast density | ||||
  Non-dense | 1(5.9) | 17(36.2) | 18(28.1) | 0.025 |
  Dence | 16(94.1) | 30(63.8) | 46(71.9) | |
 Lesion type | ||||
  Calcification | 3 (17.6) | 5 (10.6) | 8 (12.5) | 0.722 |
  Mass | 7 (41.2) | 19 (40.4) | 26 (40.6) | |
  Asymmetry/ Distortion | 7(41.2) | 23 (48.9) | 30 (46.9) | |
MRI | ||||
 Lesion type | ||||
  Mass | 17(100.0) | 37 (78.7) | 54 (84.4) | 0.038 |
  Nonmass | 0(0.0) | 10 (21.3) | 10 (15.6) | |
 Internal enhancement pattern | ||||
  Heterogeneous mass-enhancement | 4 (23.5) | 30 (63.8) | 34 (53.2) | 0.000 |
  Rim mass-enhancement | 13 (76.5) | 7 (14.9) | 20 (31.2) | |
  Line/segmental nonmass-enhancement | 0 (0.0%) | 10 (21.3) | 10 (15.6) | |
 Shape | ||||
  Regular | 6 (35.3) | 10 (21.3) | 16 (25.0) | 0.253 |
  Irregular | 11 (64.7) | 37 (78.7) | 48 (75.0) | |
 Spiculated margin | ||||
  Yes | 0 (0.0) | 16 (34.0) | 16 (25.0) | 0.005 |
  No | 17 (100.0) | 31 (66.0) | 48 (75.0) | |
 Central necrosis | ||||
  Yes | 6 (35.3) | 4 (8.5) | 10 (15.6) | 0.009 |
  No | 11 (64.7) | 43 (91.5) | 54 (84.4) | |
 Peritumoral edema | ||||
  Yes | 4 (23.5) | 10 (21.3) | 14 (21.9) | 0.847 |
  No | 13 (76.5) | 37 (78.7) | 50 (78.1) | |
 Tumor localization | ||||
  Edge | 14 (82.4) | 36 (76.6) | 50 (78.1) | 0.623 |
  Central | 3 (17.6) | 11 (23.4) | 11 (21.9) | |