Fig. 3

Identification of immune infiltration-related gene modules by WGCNA. A, B Screening of the most suitable soft threshold to build a scale-free network with ideal scale independence and mean connectivity. C Clustering dendrogram of co-expression gene modules. D The correlation between modules and traits. The correlation coefficient and p-value are presented in each cell. E Eigengene dendrogram of gene modules and immune score. F, G Correlation scatter plots of module membership and gene significance in immune infiltration-related gene modules. H The eigengene adjacency heatmap of gene modules and immune score colored by white. I Functional enrichment of immune infiltration-related gene modules by GO and KEGG analysis. The top 10 biological processes and pathways are displayed. J Cnetplot of enrichment pathways and annotated genes