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Fig. 1 | BMC Cancer

Fig. 1

From: A clinicopathological study and survival analysis of 99 breast cancers with HER2/CEP17 ratio ≥ 2.0 and an average HER2 copy number < 4.0 per cell in China

Fig. 1

Example of invasive carcinoma of no special type with HER2 immunostaining 0, 1+, and 2+ and corresponding fluorescence in-situ hybridization images. A, D, G, H&E-stained section of invasive carcinoma of no special type (original magnification ×20). B, E, H invasive carcinoma of no special type displayed HER2 IHC 0，1+ and 2+, respectively (original magnification ×20). C fluorescence in-situ hybridization image corresponding to A and B exhibited normal HER2 signals with HER2 (red)/CEP17 (green) ratio of 2.7 and average HER2 signal of 2.5. F fluorescence in-situ hybridization image corresponding to D and E displayed HER2 (red)/CEP17 (green) ratio of 4.5 and average HER2 signal of 2.5. I fluorescence in-situ hybridization image corresponding to G and H displayed HER2 (red)/CEP17 (green) ratio of 2.8 and average HER2 signal of 2.8

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BMC Cancer

ISSN: 1471-2407

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