Fig. 3

Effect of saroglitazar on liver histology (Sirius Red staining). A. Representative images of liver sections stained with Sirius Red staining and observed at 20X resolution and scale bar 40 μm. Liver sections of animals fed a normal control diet appeared to be normal. B. A score of 2–3 was assigned to the liver section of disease control animal and was considered to be moderate grade liver fibrosis (black arrow), which was reduced to minimal grade in animals treated with 3 mg/kg saroglitazar (Fig. 3A). # p < 0.0001 vs normal control, *** p < 0.001 vs disease control