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Fig. 2 | BMC Cancer

Fig. 2

From: Secreted proteins MDK, WFDC2, and CXCL14 as candidate biomarkers for early diagnosis of lung adenocarcinoma

Fig. 2

Identification of differentially expressed genes (DEGs) encoding secreted proteins using the GEO dataset GSE31210. (A) Volcano map exhibits DEGs in lung tissues of 20 normal control and 114stage IA LUAD patients in the GEO dataset GSE31210: Green plots represent the DEGs (fold change> 2; a p-value < 0.05); red plots represent genes not differentially expressed. (B) Venn diagram of upregulated DEGs in the stage IA LUAD, genes encoding secreted proteins and genes encoding proteins detectable using the Luminex assays (R&D). (C) Heatmap of the expression of 32 upregulated DEGs identified as shown in the Venn diagram

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BMC Cancer

ISSN: 1471-2407

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