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Table 1 Association between the expression of USP5 and clinicopathological parameters in NSCLC

From: EOAI, a ubiquitin-specific peptidase 5 inhibitor, prevents non-small cell lung cancer progression by inducing DNA damage

Parameter

USP5 Expression

P-value

Low (0–1)

High (2–3)

All case

19 (23.2%)

63 (76.8%)

 

Gender

  

0.5570

 Male

12 (63.2%)

35 (55.6%)

 

 Female

7 (36.8%)

28 (44.4%)

 

Age

  

0.6727

 < 60

11 (57.9%)

33 (52.4%)

 

 ≥ 60

8 (42.1%)

30 (47.6%)

 

Pathological grading

  

0.6103

 I

2 (10.5%)

6 (9.5%)

 

 II

12 (63.2%)

31 (49.2%)

 

 III

5 (26.3%)

26 (41.3%)

 

Tumor size (T)

  

0.0252a

 1

8 (42.1%)

8 (12.7%)

 

 2

9 (47.4%)

35 (55.6%)

 

 3

2 (10.5%)

16 (25.4%)

 

 4

0 (0%)

4 (6.3%)

 

EGFR

  

0.5278

 Negative

12 (92.3%)

40 (80.0%)

 

 Positive

1 (7.9%)

10 (20.0%)

 

ALK

  

0.8694

 Negative

11 (78.6%)

43 (81.1%)

 

 Positive

3 (21.4%)

10 (18.9%)

 
  1. EGFR Epidermal growth factor receptor. ALK Anaplastic lymphoma kinase
  2. a Statistically significant p-values ( p < 0.05 using chi-square test or Fisher exact tests, if appropriate)