Fig. 3
Comparison of anti-α-Gal IgE FEIA and anti-cetuximab IgE ELISA. a Results distribution for both cohorts combined (n = 185). For ELISA, in dotted line, 29 EAU threshold defined in Mariotte 2011. For FEIA, in dashed line, 0.1 kUA/L manufacturer threshold (blue), 0.35 kUA/L commonly defined threshold for sensitization (red) and 0.525 kUA/L threshold defined by a ROC curve analysis (black). b ROC curve analysis of retrospective cohort results. Comparison between anti-cetuximab IgE ELISA in dashed line (AUC = 0.864) and FEIA in full line (AUC = 0.921) (p = 0.496). Abbreviations: AUC, Area Under the Curve; ELISA, Enzyme Linked Immuno-Sorbent Assay; FEIA, Fluoroenzyme-Immunoassay; ROC, Receiver Operating Characteristic