Table 3 Univariate analysis of the severity of differentiation syndrome in patients with acute promyelocytic leukaemia

Transfusion of RBC (U)

6.5(0 ~ 16)

10.0(2 ~ 22)

−2.323

0.020

Transfusion of PLT (therapeutic volumes)

2.0(0 ~ 7)

4.0(0 ~ 12)

−2.504

0.012

D-dimer (mg/L FEU)

7.34(0.75 ~ 17.15)

14.77(0.77 ~ 40.10)

−2.177

0.030

D-dimer≥12 mg/L FEU

11.1%(1/9)

88.9%(8/9)

5.091

0.024

D-dimer< 12 mg/L FEU

69.2%(9/13)

30.8%(4/13)

WBC count on Day 3 (×10⁹/L)

7.24(0.63 ~ 60.96)

16.46(0.56 ~ 69.58)

−2.013

0.044

WBC count on Day 3 ≥ 16 × 10⁹/L

35.3%(6/17)

64.7%(11/17)

6.947

0.008

WBC count on Day 3 < 16 × 10⁹/L

74.2%(23/31)

25.8%(8/31)

WBC count at chemotherapy (×10⁹/L)

19.78(7.77 ~ 73.05)

54.62(6.24 ~ 113.20)

−3.394

0.001

WBC count at chemotherapy≥23 × 10⁹/L

36.0%(9/25)

64.0%(16/25)

13.006

0.000

WBC count at chemotherapy< 23 × 10⁹/L

87.0%(20/23)

13.0%(3/23)

LDH > 250 U/L

60.0%(18/30)

86.4%(19/22)

4.298

0.038