Table 1 Clinical characteristics in patients with acute promyelocytic leukemia at diagnosis by gender and age
Clinical characteristics | Age | Gender | Age < 60 years | Age ≥ 60 years | ||||
|---|---|---|---|---|---|---|---|---|
< 60 years (n = 75) | ≥60 years (n = 11) | Male (n = 37) | Female (n = 49) | Male | Female | Male | Female | |
Gender | ||||||||
 Male | 89.2%(33/37) | 10.8%(4/37) | – | – | – | – | – | – |
 Female | 85.7%(42/49) | 14.3%(7/49) | – | – | – | – | – | – |
WBC count at diagnosis (× 109/L) | 4.24 (0.19 ~ 192.63) | 1.2 (0.52 ~ 30.30) | 4.24 (0.19 ~ 192.63) | 3.39 (0.42 ~ 97.22) | 4.26 (0.19 ~ 192.63) | 3.57 (0.42 ~ 97.22) | 1.02 (0.84 ~ 4.26) | 2.02 (0.52 ~ 30.30) |
PLT count at diagnosis (×109/L) | 21(4 ~ 95) | 17(4 ~ 57) | 21(4 ~ 75) | 18(4 ~ 95) | 21.0(4 ~ 75) | 19(4 ~ 95) | 8(4 ~ 26) | 18(4 ~ 75) |
Risk group | ||||||||
 Low/intermediate | 83.6%(51/61) | 16.4%(10/61) | 42.6%(26/61) | 57.4%(35/61) | 43.1%(22/51) | 56.9%(29/51) | 40.0%(4/10) | 60.0%(6/10) |
 High | 96.0%(24/25) | 4%(1/25) | 44.0%(11/25) | 56.0%(14/25) | 45.8%(11/24) | 54.2%(13/24) | 0 | 100%(1/1) |
Occurrence of DS | ||||||||
 Yes | 88.7%(47/53) | 11.3%(6/53) | 39.6%(21/53) | 60.4%(32/53) | 40.4%(19/47) | 59.6%(28/47) | 33.3%(2/6) | 66.7%(4/6) |
 No | 84.4%(27/32) | 15.6%(5/32) | 46.9%(15/32) | 53.1%(17/32) | 48.1%(13/27) | 51.9%(14/27) | 40.0%(2/5) | 60.0%(3/5) |
Severity of DS | ||||||||
 mild | 90.3%(28/31) | 9.7%(3/31) | 38.7%(12/31) | 61.3%(19/31) | 39.3%(11/28) | 60.7%(17/28) | 33.3%(1/3) | 66.7%(2/3) |
 severe | 86.4%(19/22) | 13.6%(3/22) | 40.9%(9/22) | 59.1%(13/22) | 42.1%(8/19) | 57.9%(11/19) | 33.3%(1/3) | 66.7%(2/3) |
Early death | ||||||||
 Yes | 85.7%(18/21) | 14.3%(3/21) | 76.2%(16/21)* | 23.8%(5/21)* | 72.2%(13/18) * | 27.8%(5/18) * | 100%(3/3) * | 0* |
 No | 87.7%(57/65) | 12.3%(8/65) | 32.3%(21/65)* | 67.7%(44/65)* | 35.1%(20/57) * | 64.9%(37/57) * | 12.5%(1/8) * | 87.5%(7/8) * |