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Table 3 ROC-AUC, log loss, accuracy, sensitivity, and specificity results for aggressive and indolent classification on the core needle biopsy test set using transfer learning (TL) and weakly supervised learning (WS) model (TL-Colon poorly ADC (x20, 512) and WS) and fully and weakly supervised learning model (TL-Colon poorly ADC (x20, 512) and FS+WS)

From: Inference of core needle biopsy whole slide images requiring definitive therapy for prostate cancer

 

aggressive

indolent

TL-Colon poorly ADC (x20, 512) and WS

   ROC-AUC

0.970 [0.957 - 0.981]

0.851 [0.819 - 0.885]

   Log-Loss

0.410 [0.320 - 0.500]

1.133 [0.959 - 1.298]

   Accuracy

0.918 [0.898 - 0.940]

0.758 [0.727 - 0.792]

   Sensitivity

0.885 [0.846 - 0.920]

0.870 [0.798 - 0.933]

   Specificity

0.946 [0.925 - 0.968]

0.738 [0.705 - 0.777]

TL-Colon poorly ADC (x20, 512) and FS+WS

   ROC-AUC

0.980 [0.969 - 0.990]

0.846 [0.813 - 0.879]

   Log-Loss

0.213 [0.160 - 0.260]

2.273 [2.012 - 2.475]

   Accuracy

0.935 [0.918 - 0.957]

0.736 [0.707 - 0.772]

   Sensitivity

0.946 [0.919 - 0.973]

0.900 [0.833 - 0.955]

   Specificity

0.926 [0.899 - 0.955]

0.706 [0.673 - 0.750]