Fig. 10

A representative example whole slide image (WSI) of poor evaluation (diagnostic) concordance among pathologists. Histopathologically, in (A), there were wide varieties of adenocarcinoma morphology. The heatmap image (B) shows indolent prediction and (C) shows aggressive prediction. In (D), Gleason pattern 3 adenocarcinoma was predominant, which was precisely predicted as indolent (E) but not as aggressive (F). In (G), Gleason pattern 3 and 4 adenocarcinoma were mixed, which were predicted as both indolent (H) and aggressive (I). In (J), the majority of adenocarcinoma was mixed Gleason pattern 3 and Gleason pattern 4, which were predicted as both indolent (K) and aggressive (L). The model (TL-Colon poorly ADC (x20, 512) and FS+WS) predicted the WSI (A) as both indolent and aggressive. The heatmap uses the jet color map where blue indicates low probability and red indicates high probability