Table 1 Correlation between SPP1 expression and clinicopathological factors in ovarian cancer by Kaplan–Meier plotter database

Histology

 Serous

1104

553

551

1.15(1–1.33)

0.057

1207

537

670

1.29(1.1–1.5)

0.0014

 Endometrioid

51

12

39

0.43(0.16–1.15)

0.083

37

27

10

7.14(1.19–42.91)

0.012

Stage

 1

96

23

73

0.31(0.11–0.88)

0.02

74

55

19

3.04(0.94–9.81)

0.052

 2

67

40

27

1.4(0.71–2.75)

0.33

61

23

38

1.59(0.5–5.09)

0.43

 3

919

467

452

1.18(1.01–1.37)

0.036

1044

512

532

1.34(1.14–1.58)

0.00042

 4

162

94

68

1.25(0.86–1.83)

0.24

176

106

70

1.21(0.84–1.75)

0.31

Grade

 1

37

24

13

4.81(1.47–15.73)

0.0041

56

16

40

0.6(0.23–1.58)

0.29

 2

256

86

170

0.87(0.64–1.17)

0.35

324

159

165

1.41(1.04–1.92)

0.026

 3

837

414

423

1.21(1.03–1.43)

0.023

1015

452

563

1.25(1.06–1.48)

0.0078

Debulk

 Optimal

175

44

131

1.5(0.96–2.33)

0.075

189

51

138

1.72(1.07–2.77)

0.024

 Suboptimal

92

68

24

0.79(0.44–1.43)

0.43

104

48

56

1.69(1.06–2.69)

0.027

Chemotherapy

 contains platin

305

191

114

1.28(0.96–1.71)

0.088

311

100

211

1.44(1.05–2)

0.025

 contains Taxol

140

99

41

0.76(0.48–1.19)

0.23

137

49

88

2.17(1.28–3.69)

0.0034

 contains Taxol + platin

134

38

96

0.76(0.49–1.18)

0.22

131

47

84

2.21(1.28–3.81)

0.0036

 contains Gemcitabine

51

13

38

0.61(0.31–1.22)

0.16

52

30

22

0.66(0.34–1.28)

0.21