Table 2 Univariate and multivariate analysis of different prognostic variables influencing OS in HCC
From: Analysis of the expression and prognostic significance of DDK complex in Hepatocarcinoma
Variables | n | Univariate analysis | Multivariate analysis model | ||
|---|---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | ||
Gender | 0.536 (0.642–1.669) | 0.424 | |||
Male | 58 | ||||
Female | 52 | ||||
Age (year) | 0.517 (0.508–1.604) | 0.401 | |||
< 50 | 49 | ||||
≥ 50 | 61 | ||||
Tumor size (cm) | 0.637 (0.663–1.807) | 0.019 | 0.544 (0.487–1.339) | 0.011 | |
≤ 5 | 47 | ||||
> 5 | 63 | ||||
AFP(ng/ml) | 1.224 (0.403–1.353) | 0.718 | |||
≤ 20 | 45 | ||||
> 20 | 65 | ||||
HBsAg | 0.663 (0.347–1.294) | 0.667 | |||
Positive | 67 | ||||
Negative | 43 | ||||
TNM stage | 1.408 (0.574–1.397) | 0.021 | 1.307(0.610–1.547) | 0.028 | |
I/II | 49 | ||||
III/IV | 61 | ||||
Multiplicity | 0.573 (0.607–1.302) | 0.691 | |||
Single | 48 | ||||
Multiple (≥ 2) | 62 | ||||
Vascular Invasion | 1.003 (0.579–1.861) | 0.842 | |||
Presence | 56 | ||||
Absence | 54 | ||||
CDC7 expression | 1.324(0.477–1.863) | 0.011 | 1.345 (0.518–1.745) | 0.015 | |
High | 71 | ||||
Low | 39 | ||||