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Table 1 Patient characteristics

From: Afatinib plus osimertinib in the treatment of osimertinib-resistant non-small cell lung carcinoma: a phase I clinical trial

n

(%)

Age, years

Median

67

Range

50–76

Sex, n (%)

Male

4

(30.8)

Female

9

(69.2)

Smoking status

Never

6

(46.2)

Current/former

7

(53.8)

ECOG-PS, n (%)

0

5

(38.5)

1

8

(61.5)

Histology, n (%)

Adenocarcinoma

13

(100)

Clinical stage, n (%)

IVA

4

(30.8)

IVB

6

(46.2)

Recurrence

3

(23.0)

EGFR mutation, n (%)

Exon 19 deletion

4

(30.8)

+ T790M

2

(15.4)

Exon 21 L858R

4

(30.8)

+ T790M

2

(15.4)

G719C + S768I

1

(7.7)

Treatment lines, n (%)

2nd line

2

(15.4)

3rd line

5

(38.5)

≥ 4th line

6

(46.2)