STUDY PERIOD | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Pre-radiotherapy | During Radiotherapy | Post-radiotherapy | ||||||||
TIMEPOINT | 0 | Weekly | 4w | 6 m | 12 m | 18 m | 2y | 3y | 4y | 5y |
ENROLLMENT: | ||||||||||
Eligibility screening | X | |||||||||
Informed consent | X | |||||||||
Randomization | X | |||||||||
INTERVENTIONS: | ||||||||||
Omitting IMNI | X | |||||||||
With IMNI | X | |||||||||
ASSESSMENTS: | ||||||||||
Physical Examination | X | X | X | X | X | X | X | X | X | X |
Complete blood cell count | X | X | X | X | X | X | X | X | X | X |
Thyroid function | X | X | X | X | X | X | X | X | X | |
Myocardial enzyme | X | X | X | X | X | X | X | X | X | |
Chest CT scan | X | X | X | X | X | X | ||||
Mammography | X | X | X | X | X | |||||
Ultrasound for Breast and regional nodes | X | X | X | X | X | X | X | X | ||
ECG | X | X | X | X | X | X | X | X | ||
Echocardiography | X | X | X | X | X | X | X | X |