Fig. 1

Galectin-9 expression in CRC patients based on TCGA. A The expression levels of LGALS9 in different tumor types in the TCGA database (TIMER); distributions of gene expression levels are displayed using box plots. The statistical significance computed by the Wilcoxon test is indicated by the number of stars (*: p < 0.05; **: p < 0.01; ***: p < 0.001). The red box indicates the expression difference of galectin-9 in tumor tissue and adjacent tissue in colon (N = 451) and rectal cancer (N = 166); B Boxplot showing galectin-9 transcription in N0 and N1-2 samples from TCGA (LinkedOmics; N = 375), ** p < 0.01; (C) Boxplot showing galectin-9 transcription in dMMR and pMMR samples from TCGA (LinkedOmics; N = 375), ** p < 0.01