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Table 1 Content of knowledge clips in the online training module

From: Mainstream germline genetic testing in men with metastatic prostate cancer: design and protocol for a multicenter observational study

Knowledge clip

Content

1

• difference between germline and somatic pathogenic variants

• difference between genetic testing in blood and in tumor tissue

• role of pathogenic variants in carcinogenesis

2

• indications for germline genetic testing in prostate cancer

• risks of developing cancer for male and female family members with a pathogenic germline variant

• preventive measures for breast/ovarian cancer for female family members

• PSA screening for male family members carrying a pathogenic germline variant in BRCA2

3

• protocol for mainstream genetic testing

4

• advice about discussing germline genetic testing with patients

• a simulated conversation between a urologist and a patient

• an interview with a prostate cancer patient who carries a pathogenic germline variant